Cisplatin.?

What is cispltin and how does it work? Cisplatin is an antineoplastic (anti-cancer) agent that binds to nitrogen containing nucleotides during DNA replication and interferes with DNA repair mechanism. So, basically, it messes up dividing cell. Since cancer cells usually divide faster than other tissue cell do, it can selectively (partially) kill the faster growing cancer cell.
However, it will kill heathy cell that are growing. For this reason, it's side effects include mane loss and gastric lining loss- because those cell are also growing fairly speedily.
Cisplatin is dichlorodiaminoplatinum(II). It intercalates DNA and interferes with DNA replication. Normal, on form cells can sense the problem next to the DNA and either repair the DNA or put up with apoptosis. Cancer cells enjoy lost this ability, making the cancer cell much more sensitive to the chemical. This is why it kills cancer cell faster than normal cell.
Cisplatin can also be used as a sesitizer for radiation treatment.
It's one of the older chemotherapeutic agents, but it's still extremely adjectives.
Actually what rbc said is not really true. Cispt causes apoptosis of susceptible cell, regardless if they are cancer cells or not. It does this by DNA crosslinking and cause double stranded breakes, which promotes apoptosis. Cancer cells die because they are actively dividing. Most cell are not activily dividing, ie neurons. Only cells that are surrounded by synthesis phase of the cell cycle will undergo apoptosis upon cispt treatment, hence it cause G1/S arrest. The time to apoptosis and concentration of drug reqd for apoptosis is cell line dependant.
i live within new york